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작성자 Monte Madden 작성일 23-10-24 21:23

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mesothelioma is caused by exposure to (please click the up coming document) Asbestos

Mesothelioma is primarily caused by asbestos exposure. Asbestos fibers cause irritation to the lining of organs and can cause DNA damage, which what causes mesothelioma other than asbestos mesothelioma cancers.

Workers who work with asbestos can bring asbestos fibers home in their hair, clothing and other tools. This puts family members at risk of second-hand exposure. Family members may also develop mesothelioma as a result of the chemicals in their spouse's clothes.

Asbestos

Asbestos is one of the minerals that are naturally formed as small fibers. When asbestos is agitated or broken the fibers may be released into the air and then be inhaled. When this happens, the asbestos fibers can enter the smallest airways and irritate the lining of the lung (the pleura). The irritation can cause cells to grow abnormally, leading to mesothelioma tumors. Mesothelioma can also affect other areas of the body with the same lining including the peritoneum, heart, or testicles.

Medical records and other research have shown that asbestos exposure is linked to mesothelioma. Scientists aren't sure why certain people are more prone to mesothelioma than others. They have discovered that the type of asbestos used and the amount of exposure influences their risk for this type of cancer.

Chrysotile and amphibole are the most common types of asbestos associated with mesothelioma. They were used in industrial and household products, such as drywall, pipes, insulation cement, talcum powder and cement. Anyone who is exposed to these products in the workplace have the most chance of developing mesothelioma. They typically worked in industries like construction, electrical work or shipbuilding. As a result of their past, men are more likely to develop mesothelioma than women.

When asbestos fibers are introduced into the body, they stick to the organs like the chest wall, the lungs the intestines, abdomen and chest wall. Mesothelium, a durable and strong material, is able to protect against damage. When asbestos fibers cling to mesothelium they could get stuck in the tissue and remain there for years or even decades. This can cause chronic irritation, which could eventually result in mesothelioma cancer.

Like all cancers, mesothelioma can be caused by DNA mutations that cause cells grow unchecked and grow into a tumor. Researchers have identified a number of factors that increase a person's risk for developing mesothelioma. This includes an ancestor's history and prior exposure to asbestos. Mesothelioma is a rare condition and the signs and symptoms generally don't manifest until decades after exposure. People who have an exposure history should consult their physician when they experience any symptoms or signs that worry them.

Erionite

Erionite is often found in close proximity to asbestos. It is also known to cause mesothelioma, mainly pleural mesothelio. It is also associated with peritoneal pericardial mesothelioma causes. Erionite is part of the group of minerals referred to as Zeolites. Numerous morphological studies of the mineral have been carried out using electron microscopy. These studies have revealed a varied structure of the erionite fibers. The fibres can be placed in regular bundles or rod-like structures depending on the nanostructural properties of the erionite.

In a long-term study of the residents of villages exposed to erionite, Baris & Grandjean (2006) found that the mesothelioma mortality rate to be significantly higher in these villages when compared to a village that was not exposed to erionite. Over the course of 23 years in this study, 119 deaths from mesothelioma were recorded in the erionite-exposed villages and seven mesothelioma peritoneal cases were recorded. The authors concluded that the mesotheliomagenic risk of erionite was much higher than any other amphibole (antophyllite tremolite actinolite, crocidolite, and amosite), which are currently regulated under asbestos.

It is possible that the structural similarities between asbestos and erionite could be the reason behind mesothelioma. In a rat study, mesothelioma that was caused by erionite had the same cell response as asbestos-exposed rats. Furthermore, mesothelioma that was induced by erionite was correlated with an increase in Bax expression and a lower Fas ligand expression.

The Department of Transportation in North Dakota has been working with local counties and businesses to restrict the use of gravel that contains erionite. The department is continuing to monitor the erionite issue and inform citizens about it. Erionite is present in several parts of the United States, including Oregon, Idaho, and Arizona. Researchers will be able examine samples from these areas to mesotheliomagenic Erionite from Turkey in the event that they can correctly identify Erionite. This data could aid in determining how common mesothelioma is across the U.S., and may help in developing better screening and prevention strategies for workers who are exposed to this substance. It can take anywhere from 30 to 60 years for mesothelioma develop, so this research is important.

Silica

Silica or quartz is a typical industrial material found in the earth's crust. It is utilized in a variety of different settings that include mining, construction and agriculture. Based on the nature of the work, inhaling silica particles can cause debilitating and fatal lung diseases known as silicosis, or even lung cancer. Silica exposure can also increase a person's risk of developing mesothelioma. This is a deadly and potentially fatal type of lung cancer that may develop in the mesothelium.

The International Agency for Research on Cancer (IARC) and the Occupational Safety & Health Administration have both classified inhaled silica crystalline as a carcinogen. This is based upon strong evidence that inhalation exposure to silica can cause lung cancer. However the IARC does not yet acknowledge the role that silica plays in the development of different types of cancers, including mesothelioma and bladder cancer.

Mesothelioma is linked to inhalation of two types of mineral fibers that are commonly used: asbestos and mineral wool. Mesothelioma is caused by chronic irritation and aggregation of the mesothelium. Inhaling mineral fibers, such as silica and mineral wool can cause irritation to the mesothelium. Mesothelioma is more commonly diagnosed in those who are older than 45, as it takes decades for mesothelioma to develop. It is usually diagnosed in males because they have more likely than women to have held jobs that exposed them to asbestos and silica.

Asbestos and silica have been identified as lung carcinogens. Both the U.S. Environmental Protection Agency and the IARC recognize that mesothelioma and other cancers, are associated with these exposures. The underlying mechanisms that carcinogens play in the development of organ sites in other organs are not well understood. The chemistry, physics and physicochemical properties of inhaled asbestos and silica particles determine their elimination from the lung and how they are transported to other organs like the bladder.

Authors of a population-based study characterized an association between asbestos-related workplace exposure and bladder cancer based on data from the National Enhanced Cancer Surveillance System (NECSS) in eight Canadian provinces. The cohort was exposed to different asbestos dusts and silica dusts, with the highest concentrations and frequency of exposure occurring in the mining, construction, masonry, quarrying and manufacturing industries.

Other Minerals

Minerals are solid compounds that occur naturally in the Earth. They possess specific physical and chemical properties, and the majority of them have an ordinary crystal structure. Examples include the fibrous mineral asbestos, that is used to protect against fire, and barium, a soft metallic element employed in x-ray technology fireworks and rubber making. These minerals can be found on personal or clothing items brought home by workers. Family members could be exposed to asbestos fibers.

Asbestos is known to cause mesothelioma develop in 70 to 80 percent of all cases diagnosed. A small proportion of cases were attributed to exposure to other minerals than asbestos. These minerals include erionite, other forms of silica as well as non-asbestiform grunerite utilized in mining operations.

The chest is where mesothelioma symptoms typically begin. They can include swelling, pain and difficulty breathing. The disease most commonly develops in the pleura that protects your diaphragm and the lungs. The disease can also develop in the peritoneum, which is a part of your stomach and the intestinal tract. In certain instances, mesothelioma may be spread to other parts of your body.

In general, it can take 20 years or more for pleural mesothelioma develop after asbestos exposure. Due to this, Mesothelioma is Caused by Exposure to a lot of affected people don't seek medical help until they experience a significant symptom such as persistent chest pain or a build-up of fluid in the lungs.

The type of treatment you receive for mesothelioma depends on the severity of your condition and how far it has spread. For instance, your doctor might recommend treatments to ease symptoms and prolong your life. This may include draining fluid from your lungs, or taking strong painkillers to ease your discomfort.

Your doctor will prescribe medications to alleviate your symptoms and fight cancer cells. The most common treatment for the pleural msothelioma is chemotherapy. It can be used as a stand-alone treatment or in combination with other therapies. Other treatments include surgery and radiation. Surgery could involve the removal of your lung or a portion of your diaphragm. Or, it could be combined with chemotherapy and radiation.